Antidiabetic Screening of Methanolic Stem Extract of Opuntia Ficus Indica on Experimental Subjects

Abstract

Diabetes Mellitus is a group of symptoms caused by hyperglycemia and changes in lipid, carbohydrate and protein metabolism, increasing the risk of vascular diseases. More than 400 herbs have been reported to have hypoglycemic effects, but only some of them have been studied. Although there are many medications to control diabetes, they also have some side effects. Opuntia Ficus Indica is famous in the Ayurvedic system of medicine and is used to treat many ailments. The plant is reported to have laxative, antiasthmatic, anthelminthic, headache, antiseptic and anti-inflammatory properties. This study aimed to investigate the anti-diabetic effect of cactus stem extract on alloxan-induced diabetic rats. This study focuses on the Prickly Pear model and evaluates its anti-inflammatory activity, focusing on its mechanism of action. Validation of antidiabetic properties is related to many biochemical parameters involved.