Evaluating the Impact of Metformin and Vitamin B12 Levels in the Treatment of Diabetes

Abstract

Background: Metformin is an oral anti-diabetic drug used as a treatment for type 2 diabetes. It is the medication for this illness that is most often recommended, and it works well to reduce blood glucose levels. Metformin works by reducing the amount of glucose the liver produces and improving how responsive the body's cells are to insulin. Moreover, it lessens the quantity of glucose that the intestine absorbs from meals. According to recent studies, metformin may help manage diabetes by raising levels of vitamin B12. A water-soluble vitamin, vitamin B12 is crucial for the body's energy and metabolism production. Low levels of vitamin B12 can lead to anaemia, fatigue, nerve damage, and other health problems. Studies have shown that Metformin can increase levels of vitamin B12 in patients with diabetes. This may be because Metformin reduces the amount of glucose in the blood, which allows the body to better absorb vitamin B12 from food sources. Additionally, Metformin may help to reduce inflammation in the body, which can help to improve the absorption of vitamin B12.

Methods: Analysis of primary research articles written in any language. Type -2 diabetes pharmacology and diagnosis and their synonyms were used to search the Web of Science, PsycINFO, and PubMed, databases. According to the synthesis without meta-analysis in systematic reviews, a narrative synthesis was conducted.