To Formulate 60 Laxative Suppositories Using Glucogelatin Base and Perform All Quality Tests

Riya Rana — 2026-07-29

This study developed glycerogelatin suppositories using only glycerin as the laxative, with no added drugs. Constipation is common, and rectal delivery helps patients who can’t take oral meds. Suppositories act fast, avoid part of first-pass metabolism, and suit kids and the elderly. The fusion method was used with gelatin, glycerin, and water. Glycerin worked as both plasticizer and osmotic laxative, drawing water into the rectum to soften stool. Tests for appearance, weight, hardness, softening time, disintegration, and stability showed uniform, stable suppositories. Glycerogelatin proved suitable, and glycerin alone gave an effective, low-cost option for constipation with good patient compliance. The results demonstrated that the suppositories were uniform and stable, with acceptable physical and performance characteristics. The study confirmed that glycerogelatin base is suitable for suppository formulation and that glycerine alone can effectively produce a laxative effect. Overall, the formulation provides a simple, economical, and effective approach for the management of constipation, with good patient compliance and therapeutic reliability.

Formulation and Evaluation of Herbal Face Scrub Utilizing Citrus Peel Waste

Marathe Shruti Kakasaheb — 2026-08-07

The increasing demand for eco-friendly and herbal cosmetic products has encouraged the exploration of natural resources and sustainable ingredients. Citrus peel by-products, rich in bioactive compounds such as flavonoids, essential oils, and antioxidants, offer significant potential for cosmetic applications. The present study focuses on the formulation and evaluation of a herbal face scrub utilizing citrus peel by-products as a natural exfoliating agent. Citrus peels were collected, dried, and processed into a fine powder, which was incorporated into the scrub formulation along with other herbal ingredients such as rice flour, flaxseed powder, and camphor powder. Rice flour acts as a mild exfoliant and helps in skin brightening, while flaxseed powder provides moisturizing and soothing effects due to its rich omega fatty acid content. Camphor powder contributes cooling, antimicrobial, and refreshing properties to the formulation. These ingredients collectively enhance the cleansing, exfoliating, and skin-nourishing effects of the scrub. The prepared formulation was evaluated for various physicochemical parameters including pH, viscosity, spreadability, consistency, and stability. Additionally, the scrub was assessed for its exfoliating efficiency, skin compatibility, and irritation potential.

Journal of Advances in Pharmacy Practices (e-ISSN: 2582-4465)

To Formulate 60 Laxative Suppositories Using Glucogelatin Base and Perform All Quality Tests

Formulation and Evaluation of Herbal Face Scrub Utilizing Citrus Peel Waste