An Overview of Nanoparticles from Plant Origin with Cytotoxic Potential

Authors

  • R. Mythreyi Chettinad School of Pharmaceutical Sciences
  • Ma. Victoria E. Mendoza
  • Preligera
  • Marielle D. Ramirez
  • Ann Airabell O. Sabigan
  • Lovely Justine P. Sanguellas
  • Danica S. Salva Wylyn S

Keywords:

Cytotoxic potential, Green synthesized, Nanoparticles NP, Phyto nanomedicine, Targeted drug delivery

Abstract

Background/Objective: This study provides an overview of nanoparticles derived from plant sources, emphasizing their cytotoxic potential and applications in cancer treatment. Recent advancements in nanotechnology have highlighted the advantages of plant-based nanoparticles, which are synthesized using eco-friendly methods that harness the natural phytochemicals of plants. These nanoparticles inherit unique physical and chemical properties from the plant material, making them suitable for various biomedical applications. Methods: The research explores the mechanisms by which plant-derived nanoparticles exhibit significant cytotoxicity against various cancer cell types, primarily through the induction of oxidative stress and programmed cell death while sparing normal cells. Results: Furthermore, the study discusses the innovative potential of these nanoparticles in targeted drug delivery, which can enhance therapeutic efficacy and minimize the adverse effects commonly associated with traditional chemotherapy. Conclusion: As the understanding of their composition, size, and surface characteristics is refined, plant-based nanoparticles represent a promising avenue for developing safer and more effective cancer therapies. This review underscores the importance of further research in this promising area of nanomedicine.

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Published

2025-03-01