Antidiabetic Screening of Methanolic Stem Extract of Vitex negundo on Experimental Subject

Abstract

Diabetes is a group of symptoms caused by high blood sugar and lipid, carbohydrate, and protein metabolism changes that increase the risk of vascular disease. More than 400 herbs have been reported to have hyperglycemic effects, but only some have been studied. Although there are many medications to control diabetes, they also have some side effects. Vitex negundo is famous in the Ayurvedic system of medicine and is used to treat many ailments. The plant has laxative, antiasthmatic, antihelminthic, headache, antiseptic, and anti-inflammatory properties. This study aimed to investigate the anti-diabetic effect of plant stem extract on alloxan-induced diabetic rats. Recognition of anti-diabetic drugs is related to many biochemical parameters.