Review of Mouth Dissolving Tablets, Specially Emphasis on Formulation

Authors

  • Pankaj Khuspe
  • Jagtap Sakshi Hari
  • Pawar Rajnandini Rajendra
  • Shaikh Salona
  • Hange Rituja Baban
  • Mane Rushikesh Bandu

Keywords:

Bioavailability, Formulation technology, Mouth Dissolving Tablets (MDTs), Oral drug delivery, Patient compliance

Abstract

About pharmaceutical formulations, mouth-dissolving tablets (MDTs) have become a paradigm shift that offers a way around the problems with conventional oral drug delivery methods. This thorough analysis explores the terrain of MDTs, clarifying their development, formulation complexities, and therapeutic uses. In light of the challenges of traditional tablets, this investigation aims to comprehend the distinct attributes that characterize MDT. The story begins with a look at the early advancements and historical trajectory of MDT technology, emphasizing significant turning points that have influenced the field's development. Following is a thorough examination of the formulation features, including information on the essential components, excipients, and manufacturing processes that support the creation and development of MDTs. MDTs are known for their unique qualities, and this research carefully examines the disintegration mechanisms, dissolving profiles, and taste-masking techniques used. Investigating stability factors and palatability enhancement offers a comprehensive understanding of the chemical and physical characteristics of MDTs. When MDTs are used with various patient populations, it is clear how versatile they are. In particular, how they can help with the problems that youngsters, the elderly, bedridden patients, and other unique populations confront is explored. As the study progresses, it considers the opportunities and difficulties that MDT research will face in the future. New developments embody the forward-looking viewpoint in formulation methodologies, possible uses in innovative therapeutic domains, and continuous efforts to overcome obstacles.

Published

2024-02-08