Synthesis and Characterization of Novel Fluorinated Pyrimidine Heterocyclic Derivatives as Pharmaceutical Agents

Abstract

Fluorinated pyrimidine derivatives represent a broad class of compounds that have received much attention owing to their wide range of applications such as pharmaceutical agents, anti-cancer, antimicrobial, antidepressant, antioxidant, antidiabetic, antiviral, antifungal, anti-herpes, and anti-tumor agents. Due to these pharmaceutical applications associated with fluorinated pyrimidines, we decided to synthesize them. Fluorinated pyrimidines have been synthesized via a one-pot multicomponent approach. All synthesized have been purified and characterized.