A Review on Evaluation of Wound Healing Potential of Lawsonia inermis and Acalypha indica: A Synergistic Study
Keywords:
Acalypha Indicia, Indian traditional medicine, Lawsonia Inermis, Wound healingAbstract
The dry coastal scrublands of North Africa, the Middle East, and areas of southern Asia are home to the henna plant, Lawsonia Inermis. It is the most recognised plant in the Lythraceae family. In Native to India, Indochina, Ethiopia and other tropical and subtropical countries, Acalypha indica is also referred to as Indian copper leaf. It is used in traditional medicine for a number of ailments and is a member of the Euphorbiaceae family. The medicinal efficacy of aqueous and various chemical extracts of Lawsonia inermis and Acalypha Indica has been the subject of numerous studies. Therefore, the pharmacological potential of dried leaves of Lawsonia inermis and Acalypha Indica has not been investigated together from a pharmacological and phytochemical standpoint. Each of these plants has been shown to have wound-healing properties. In order to demonstrate and improve the wound healing activity in comparison to the separate and individual evaluations, the purpose of this study was to provide pertinent information on the extraction of both plants and their combination. The leaves, barks, roots, and seeds of Acalypha Indica and Lawsonia inermis are utilized as potential Ayurvedic and traditional medicines all across the world. Several methods are used to extract Lawsonia inermis and Acalypha Indica. In addition to triterpenoids, steroids, aliphatic hydrocarbons, proteins, alkaloids, quinones, xanthones, fats, and resins, other substances include lawsone, flavonoids, coumarins, tannins, and phenolic chemicals including Gallic acid derivatives and naphthalene. The primary chemical components found in both plants include, acalyphine Kaempferol glycosides, tannins, β-sitosterol, acalyphamide, aurantiamide succinimide, flindersin, isoiridomyrmecin, and isodihydro-nepetalactone. The antibacterial, antifungal, antitumor and antiproliferative, antiangiogenic, antileishmanial, lousicide, antimalarial, hepatoprotective, wound healing, antiinflammatory, analgesic, antipyretic, memory enhancement, enzyme inhibitor and antioxidant, and anti-ulcer properties of Lawsonia inermis and Acalypha Indica have been confirmed by clinical and experimental studies. This is the first attempt to collect data regarding the addition of Lawsonia inermis and Acalypha Indica to increase their wound-healing activities. Future scientific studies will require more investigation.
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