Journal of Clinical Trials and Regulations (e-ISSN: 2582-4422)

An Informatics Analysis over the Last Ten Years Focused on Community Pharmacy-Based Research in India

Vinay Gaikwad — 2024-04-15

This research began to capture and evaluate the available data on Indian community pharmacy practice over the previous ten years (2013–2023). To evaluate the many facets of community pharmacy-based practice in India, an informatics evaluation study of the original publications was conducted. The data sources included periodicals like the Indian Journal of Hospital Pharmacy and the Indian Journal of Pharmaceutical Sciences as well as databases like MEDLINE, Index Copernicus, IndMed, and DOAJ. Analyses were done on the publications' impact factor, the kind of work, the category of journals, the category of articles, and the indices of production.

In the current investigation, fifteen articles were included out of which forty-three percent of the articles were released in the Indian Journal of Hospital Pharmacy out of twenty-one publications. 3.86 authors on average (SD=1.38) were included in a publication. There were just five journals that had an impact factor.

Limited research on community pharmacy-related activities in India is being published in Indian journals. Some essential difficulties to the growth of the local pharmacist function in India are presented by the main indicators that arise from the literature study. In contrast to the preceding five years, there was advancement in this sector after 2019–20.

Evaluating the Effectiveness of Medication Therapy Management Services

S. Prathamesh Kumar Suresh Ithape — 2024-01-30

This research aims to comprehensively evaluate the effectiveness of Medication Therapy Management (MTM) services in optimizing patient outcomes and enhancing medication-related processes. MTM, a patient-centric approach delivered by pharmacists, involves assessing and managing medication regimens to improve therapeutic outcomes while minimizing adverse effects. The study employs a mixed-methods design, combining quantitative measures and qualitative insights to provide a holistic understanding of MTM services. The quantitative phase involves analyzing medication-related data, including adherence rates, changes in health indicators, and healthcare utilization patterns among patients receiving MTM services compared to those without such interventions. Statistical analyses, such as multivariate regression models, will be employed to identify significant associations. In the qualitative phase, in-depth interviews will be conducted with both patients and pharmacists delivering MTM services. This qualitative approach aims to capture nuanced perspectives, exploring patient experiences, satisfaction levels, and the perceived impact of MTM on their overall health and well-being. Pharmacists’ insights into the challenges and successes of MTM implementation will also be explored. The research will focus on diverse patient populations, considering variations in age, health conditions, and socioeconomic backgrounds. By examining the effectiveness of MTM across different demographic groups, the study aims to identify potential variations in outcomes and tailor recommendations for personalized care. Anticipated outcomes include a nuanced understanding of the impact of MTM services on patient medication adherence, health outcomes, and healthcare utilization. The study will contribute valuable insights to healthcare providers, policymakers, and pharmacists seeking to enhance patient-centred care through the optimization of medication therapy management. The findings of this research hold the potential to inform future healthcare policies and practices, emphasizing the pivotal role of pharmacists in ensuring medication safety, efficacy, and patient satisfaction. As healthcare systems continue to evolve towards value-based care, evaluating and optimizing MTM services becomes crucial in achieving the overarching goal of improving patient outcomes and the overall quality of healthcare delivery.

Phytochemicals as Novel Therapeutic Agents for Treating Chronic Diseases: Efficacy, Safety, and Clinical Considerations

Vishal Gajanan Murkute — 2024-04-10

Phytochemicals, derived from plants, are increasingly recognized for their potential therapeutic benefits in managing chronic diseases. This review aims to assess their efficacy, safety, and clinical considerations. Phytochemicals exhibit diverse biological activities, including antioxidant, anti-inflammatory, and anticancer properties, which make them promising candidates for adjunctive therapy or preventive measures against chronic conditions. However, the efficacy of phytochemicals varies depending on factors such as dosage, bioavailability, and patient population. Safety concerns, including potential toxicity and interactions with medications, warrant careful evaluation and monitoring. Furthermore, clinical studies exploring the efficacy of phytochemicals in chronic disease management are essential for evidence-based recommendations. Despite promising preclinical findings, the translation of phytochemicals into clinical practice requires rigorous investigation to establish their effectiveness and safety profiles. Additionally, considerations such as standardization of formulations and regulatory aspects are crucial for ensuring quality and consistency in phytochemical-based therapeutics while phytochemicals are potential novel therapeutic agents for chronic diseases, further research is necessary to elucidate their optimal use and integration into clinical practice.