To Explore the Protective Potential of Amaranthus viridis and Azadirachta indica in Combating Retinal Degeneration Associated with Retinitis Pigmentosa

Gulam Husain Niyazi, Arvind kumar Srivastava, Pranshu Tripathi, Shivaansh Tiwari — Fri, 17 Jul 2026 00:00:00 +0000

Retinitis pigmentosa is an inherited disorder of the retina characterised by a gradual loss of vision due to the destruction of photoreceptor cells. There are currently no clinically useful therapies available for this disease. Factors contributing to the progression of retinitis pigmentosa include oxidative stress, inflammation, and neuronal injury. Due to their bioactive compounds with potential protective effects, there has been increasing interest in using plants as treatments for this disease. Amaranthus viridis is known for its high antioxidant capacity, which decreases oxidative stress and protects cells from damage caused. The anti-inflammatory and neuroprotective properties of Azadirachta indica could help protect retinal cells from death. The purpose of this project is to determine whether Amaranthus viridis and Azadirachta indica can offer protection from retinal degeneration caused by retinitis pigmentosa by investigating their antioxidant and neuroprotective capabilities in regulating the progression of retinitis pigmentosa and preserving retinal function. The results from this study could promote further experimental and clinical research, while also providing insight into the use of natural, plant-based sources as adjunct therapeutic modalities in the management of retinitis pigmentosa.

Phytochemical Diversity, Ethnomedicinal Significance, and Pharmacological Potential of Litsea monopetala: A Comprehensive Review

Abdullah Al Faruq, Irin Sultana, Suhana Manzur Chowdhury, Md. Effadul Islam Econ — Mon, 20 Jul 2026 00:00:00 +0000

Litsea monopetala, belonging to Lauracea plant family, is a widely distributed, traditionally used plant. The plant is specially located in South and Southeast Asia. The plant contains many important phytochemicals including citral, β-caryophyllene, linalool, and other phenolic compounds which contributed its phytochemical and biological activities. Some notable therapeutic activities of the plant species include ant-microbial, anti-oxidant, anti-inflammatory, analgesic, anti-diarrhoeal, cytotoxic potential etc. Many studies revealed that the plant derived compounds show medicinal activities by modulating TNF-α, IL-6, COX-2, and GABAergic pathways. Additionally, the plant has gained increasing scientific attention because of its broad pharmacological profile and rich reservoir of bioactive secondary metabolites. Various parts of the plant, including the leaves, bark, roots, and fruits, have been investigated for their therapeutic potential. Experimental findings suggest that its extracts may possess immunomodulatory, hepatoprotective, and neuroprotective properties, which could be attributed to the synergistic action of flavonoids, alkaloids, terpenoids, and essential oils. The diverse phytochemical composition of the plant supports its traditional applications and highlights its potential as a promising source for the development of novel plant-based therapeutic agents. However, most of the studies conducted on this plant species were based on in-viro and in-vivo models. So, advanced research is required to validate its traditional uses.

International Journal of Phyto Pharmaceutics and Research

To Explore the Protective Potential of Amaranthus viridis and Azadirachta indica in Combating Retinal Degeneration Associated with Retinitis Pigmentosa

Phytochemical Diversity, Ethnomedicinal Significance, and Pharmacological Potential of Litsea monopetala: A Comprehensive Review