Fuzzy Logic-Based Medical Diagnosis System for Handling Uncertainty in Healthcare Data

Authors

  • Nisha Rathore
  • Vinay Kumar Singh
  • Shikha Tiwari
  • Pari Jain

Keywords:

Decision support systems, Fuzzy Inference System (FIS), Fuzzy logic, Healthcare AI, Medical diagnosis, Uncertainty modeling

Abstract

Medical diagnosis has always been characterised by its inherent uncertainty due to the lack of precision associated with various symptoms, the differences that exist between patients, and the incompleteness of clinical information available. Traditional decision-making models based on crisp/logical reasoning do not adequately account for such a large amount of uncertainty. In contrast to the use of traditional decision-making models, fuzzy models represent the best method for dealing with vagueness by incorporating linguistic variables (e.g., 'very low' or 'moderate', etc.) and approximate reasoning. This paper focuses on a specific fuzzy logic-based system designed for use within a medical diagnosis application. The system uses fuzzy logic inference mechanisms to map patient inputs (e.g., symptom data, medical history) to the level of severity of the disease (e.g., mild, moderate, severe), and is comprised of the following components: fuzzification; construction of a rule base; model for inference; and defuzzification. The mathematical development, modeling of membership functions, and analysis of this system are presented in detail. The findings from experimentation suggest that the accuracy, interpretability, and robustness of this fuzzy logic-based system are much greater than those of more traditional methods. Therefore, the results of this work point to the efficacy of fuzzy models in supporting real-world healthcare decision-making systems.

References

T. Senapati and R. R. Yager, “Fermatean fuzzy sets,” Journal of Ambient Intelligence and Humanized Computing, vol. 11, no. 2, pp. 663–674, Feb. 2020.

A. Gad and M. Farooq, “Application of fuzzy logic in engineering problems,” in Proceedings of the 27th Annual Conference of the IEEE Industrial Electronics Society (IECON), vol. 3, Nov. 2001, pp. 2044–2049.

J. S. R. Jang, “ANFIS: Adaptive-network-based fuzzy inference system,” IEEE Transactions on Systems, Man, and Cybernetics, vol. 23, no. 3, pp. 665–685, Jun. 1993.

N. Rathore and M. P. Singh, “Selection of optimal renewable energy resources in uncertain environment using ARAS-Z methodology,” in Proceedings of the International Conference on Communication and Electronics Systems (ICCES), IEEE, Jul. 2019, pp. 373–377.

C. T. Lin and C. S. Lee, “Neural-network-based fuzzy logic control and decision system,” IEEE Transactions on Computers, vol. 40, no. 12, pp. 1320–1336, Aug. 2002.

S. K. Pal and S. Mitra, Neuro-fuzzy pattern recognition: Methods in soft computing. New York, NY, USA: John Wiley & Sons, Inc., Sep. 1999.

N. Rathore, D. K., and M. P. Singh, “Selection of optimal renewable energy resources using TOPSIS-Z methodology,” in Proceedings of the International Conference on Advanced Communication and Computational Technology, Singapore: Springer Nature Singapore, Dec. 2019, pp. 967–977.

K. Tanaka and H. O. Wang, Fuzzy control systems design and analysis: A linear matrix inequality approach. Hoboken, NJ, USA: John Wiley & Sons, Mar. 2004.

E. H. Mamdani, “Application of fuzzy algorithms for control of simple dynamic plant,” Proceedings of the Institution of Electrical Engineers, vol. 121, no. 12, pp. 1585–1588, Dec. 1974.

J. M. Mendel, “Fuzzy logic systems for engineering: A tutorial,” Proceedings of the IEEE, vol. 83, no. 3, pp. 345–377, Aug. 2002.

R. I. John and P. R. Innocent, “Modeling uncertainty in clinical diagnosis using fuzzy logic,” IEEE Transactions on Systems, Man, and Cybernetics Part B: Cybernetics, vol. 35, no. 6, pp. 1340–1350, Nov. 2005.

N. H. Phuong and V. Kreinovich, “Fuzzy logic and its applications in medicine,” International Journal of Medical Informatics, vol. 62, no. 2–3, pp. 165–173, Jul. 2001.

H. Ahmadi, M. Gholamzadeh, L. Shahmoradi, M. Nilashi, and P. Rashvand, “Diseases diagnosis using fuzzy logic methods: A systematic and meta-analysis review,” Computer Methods and Programs in Biomedicine, vol. 161, pp. 145–172, Jul. 2018.

E. Vlamou and B. Papadopoulos, “Fuzzy logic systems and medical applications,” AIMS Neuroscience, vol. 6, no. 4, p. 266, Oct. 2019.

N. Nishant, N. Rathore, V. K. Nassa, V. K. Dwivedi, and S. P. Dillibabu, “Integrating machine learning and mathematical programming for efficient optimization of electric discharge machining technique,” The Scientific Temper, vol. 14, no. 3, pp. 859–863, Sep. 2023.

G. Arji, H. Ahmadi, M. Nilashi, T. A. Rashid, O. H. Ahmed, N. Aljojo, and A. Zainol, “Fuzzy logic approach for infectious disease diagnosis: A methodical evaluation, literature and classification,” Biocybernetics and Biomedical Engineering, vol. 39, no. 4, pp. 937–955, Oct. 2019.

M. Dhipa, N. Rathore, P. P. Adivarekar, and S. T. Siddiqui, “Enhancing energy efficiency in sensor/ad-hoc networks through dynamic sleep scheduling,” ICTACT Journal on Communication Technology, vol. 14, no. 3, Sep. 2023.

V. Prasath, N. Lakshmi, M. Nathiya, N. Bharathan, and P. Neetha, “A survey on the applications of fuzzy logic in medical diagnosis,” International Journal of Scientific and Engineering Research, vol. 4, no. 4, pp. 1199–1203, Apr. 2013.

A. A. Sadat Asl and M. H. Zarandi, “A type-2 fuzzy expert system for diagnosis of leukemia,” in Proceedings of the North American Fuzzy Information Processing Society Annual Conference, Cham: Springer International Publishing, Sep. 2017, pp. 52–60.

N. Rathore, P. B. Acharjee, K. Thivyabrabha, and A. Ingle, “Researching brain-computer interfaces for enhancing communication and control in neurological disorders,” The Scientific Temper, vol. 14, no. 4, pp. 1098–1105, Dec. 2023.

P. Chinniah and D. S. Muttan, “ICD 10 based medical expert system using fuzzy temporal logic,” Arxiv Preprint Arxiv:1001.1979, Jan. 2010.

M. S. Ibrahim and D. W. Al-Dulaimee, “Design multimedia expert diagnosing diseases system using fuzzy logic (MEDDSFL),” arXiv preprint arXiv:2003.09963, Mar. 2020.

N. Rathore, G. Soni, B. Khandelwal, R. Kashyap, B. P. Kasaraneni, and R. Nair, “Leveraging AI and blockchain for scalable and secure data exchange in IoMT healthcare ecosystems,” in Proceedings of the 4th OPJU International Technology Conference (OTCON) on Smart Computing for Innovation and Advancement in Industry 5.0, IEEE, Apr. 2025, pp. 1–6.

C. D. Stylios and V. C. Georgopoulos, “Fuzzy cognitive maps structure for medical decision support systems,” in Forging New Frontiers: Fuzzy Pioneers II, Berlin, Heidelberg: Springer Berlin Heidelberg, 2008, pp. 151–174.

Published

2026-04-17