Next-Gen Healthcare: Machine Learning-Based Chronic Kidney Disease Prediction
Keywords:
Chronic Kidney Disease (CKD), Clinical decision support, Early disease prediction, Healthcare AI, Machine Learning (ML), Medical data analyticsAbstract
Chronic Kidney Disease (CKD) is a major global health issue that is often detected at later stages due to a lack of early screening methods. Traditional diagnosis depends on laboratory tests and doctors' expertise, which can sometimes delay timely treatment. Machine Learning (ML) is transforming healthcare by improving early disease detection and prediction accuracy. This study focuses on ML-based models for CKD prediction, using patient medical records and clinical data to improve diagnosis. Different ML techniques, including Decision Trees, Random Forest, Support Vector Machines, and Deep Learning, are analyzed to find the most effective approach. To improve model performance, data preprocessing methods such as feature selection, normalization, and handling of missing values are applied. The findings show that ML models perform much better than traditional diagnostic methods, achieving high accuracy, precision, recall, and AUC-ROC scores. Ensuring that these models are interpretable and explainable is essential for their practical use in healthcare. While challenges like data imbalance and biases exist, ML-based CKD prediction systems offer great potential for real-world applications, allowing for early detection and personalized treatment. This research highlights how ML can revolutionize healthcare by enabling automated, data-driven diagnostic solutions. Future improvements will focus on strengthening model reliability, exploring deep learning methods, and integrating ML predictions into clinical decision-making tools. Advancing AI-driven healthcare solutions can significantly improve patient care, reduce CKD-related complications, and lower mortality rates.
References
Md. A. Islam, Md. Z. H. Majumder, and Md. A. Hussein, “Chronic kidney disease prediction based on machine learning algorithms,” Journal of Pathology Informatics, p. 100189, Jan. 2023, doi: https://doi.org/10.1016/j.jpi.2023.100189.
D. A. Debal and T. M. Sitote, “Chronic kidney disease prediction using machine learning techniques,” Journal of Big Data, vol. 9, no. 1, Nov. 2022, doi: https://doi.org/10.1186/s40537-022-00657-5.
P. Chittora, S. Chaurasia, P. Chakrabarti, G. Kumawat "Prediction of Chronic Kidney Disease - A Machine Learning Perspective," in IEEE Access, vol. 9, pp. 17312-17334, 2021, doi: https://doi.org/10.1109/ACCESS.2021.3053763
M. Rashed-Al-Mahfuz, A. Haque, A. Azad, S. A. Alyami, J. M. W. Quinn and M. A. Moni, "Clinically Applicable Machine Learning Approaches to Identify Attributes of Chronic Kidney Disease (CKD) for Use in Low-Cost Diagnostic Screening," in IEEE Journal of Translational Engineering in Health and Medicine, vol. 9, pp. 1-11, 2021, Art no. 4900511, doi: https://doi.org/10.1109/JTEHM.2021.3073629
J. Xiao ,R. Ding, X. Xu, H. Guan, “Comparison and development of machine learning tools in the prediction of chronic kidney disease progression,” Journal of Translational Medicine, vol. 17, no. 1, Apr. 2019, doi: https://doi.org/10.1186/s12967-019-1860-0.
S. Akter ,A. Habib, M. A. Islam, M. D. Hossen, "Comprehensive Performance Assessment of Deep Learning Models in Early Prediction and Risk Identification of Chronic Kidney Disease," in IEEE Access, vol. 9, pp. 165184-165206, 2021, doi: https://doi.org/10.1109/ACCESS.2021.3129491
D. Chicco, C. A. Lovejoy and L. Oneto, "A Machine Learning Analysis of Health Records of Patients With Chronic Kidney Disease at Risk of Cardiovascular Disease," in IEEE Access, vol. 9, pp. 165132-165144, 2021, doi: https://doi.org/10.1109/access.2021.3133700
J. Qin, L. Chen, Y. Liu, C. Liu, C. Feng and B. Chen, "A Machine Learning Methodology for Diagnosing Chronic Kidney Disease," in IEEE Access, vol. 8, pp. 20991-21002, 2020, doi: https://doi.org/10.1109/access.2019.2963053
R. K. Halder, M. S. Uddin, M. A. Uddin, S. Aryal, “ML-CKDP: Machine learning-based chronic kidney disease prediction with smart web application,” Journal of pathology informatics, vol. 15, pp. 100371–100371, Dec. 2024, doi: https://doi.org/10.1016/j.jpi.2024.100371.
F. Sanmarchi, C. Fanconi, D. Golinelli, D. Gori, T. Hernandez-Boussard, and A. Capodici, “Predict, diagnose, and treat chronic kidney disease with machine learning: a systematic literature review,” Journal of Nephrology, Feb. 2023, doi: https://doi.org/10.1007/s40620-023-01573-4.
Md. Mehedi Hassan et al., “A Comparative Study, Prediction and Development of Chronic Kidney Disease Using Machine Learning on Patients Clinical Records,” Human-Centric Intelligent Systems, vol. 3, pp. 92–104, Feb. 2023, doi: https://doi.org/10.1007/s44230-023-00017-3.
Z. Ye S. An, Y. Gao, E. Xie, X. Zhao, “The prediction of in-hospital mortality in chronic kidney disease patients with coronary artery disease using machine learning models,” European Journal of Medical Research, vol. 28, no. 1, Jan. 2023, doi: https://doi.org/10.1186/s40001-023-00995-x
N. Lei, X. Zhang, M. Wei, B. Lao, X. Xu, M. Zhang,“Machine learning algorithms’ accuracy in predicting kidney disease progression: a systematic review and meta-analysis,” BMC Medical Informatics and Decision Making, vol. 22, no. 1, Aug. 2022, doi: https://doi.org/10.1186/s12911-022-01951-1.
S. U. Habiba, F. Tasnim, M. Saeed, M. K. Islam, L. Nahar, “Early Prediction of Chronic Kidney Disease Using Machine Learning Algorithms with Feature Selection Techniques,” Communications in computer and information science, pp. 224–242, Jan. 2024, doi: https://doi.org/10.1007/978-3-031-68639-9_14.
M. U. Emon, A. M. Imran, R. Islam, M. S. Keya, R. Zannat and Ohidujjaman, "Performance Analysis of Chronic Kidney Disease through Machine Learning Approaches," 2021 6th International Conference on Inventive Computation Technologies (ICICT), Coimbatore, India, 2021, pp. 713-719, doi: https://doi.org/10.1109/ICICT50816.2021.9358491.
S. M. M. Elkholy, A. Rezk and A. A. E. F. Saleh, "Early Prediction of Chronic Kidney Disease Using Deep Belief Network," in IEEE Access, vol. 9, pp. 135542-135549, 2021, doi: https://doi.org/10.1109/ACCESS.2021.3114306